The primary interest of my research group is in cartilage tissue engineering. Our current research activities cover the whole spectrum from basic science to clinical translation. Our main challenge is to be able to produce cartilage of the normal phenotype with the appropriate biochemical, structural and biomechanical properties. Our strategy is to improve mesenchymal stem cell chondrogenesis through the manipulation of various factors such as genes, signaling pathways, extracellular matrix components, mechanical stimulation and the use of biomimetic scaffolds. We are currently carrying out clinical trials for cartilage repair and regeneration.
Department of Orthopaedic Surgery
1E, Kent Ridge Road
NUHS Tower Block, Level 11